WASHINGTON — President Biden, beneath strain to aggressively deal with the worldwide coronavirus vaccine scarcity, will announce as early as Thursday that his administration will purchase 500 million doses of the Pfizer-BioNTech vaccine and donate them amongst about 100 international locations over the subsequent yr, in accordance with individuals aware of the plan.

The White Home reached the deal simply in time for Mr. Biden’s eight-day European trip, which is his first alternative to reassert the US as a world chief and restore relations that have been badly frayed by President Donald J. Trump.

“We now have to finish Covid-19, not simply at dwelling, which we’re doing, however in every single place,” Mr. Biden told American troops after touchdown at R.A.F. Mildenhall in Suffolk, England. “There’s no wall excessive sufficient to maintain us protected from this pandemic or the subsequent organic menace we face, and there can be others. It requires coordinated multilateral motion.”

Individuals aware of the Pfizer deal mentioned the US would pay for the doses at a “not for revenue” worth. The primary 200 million doses can be distributed by the top of this yr, adopted by 300 million by subsequent June, they mentioned. The doses can be distributed by way of Covax, the worldwide vaccine-sharing initiative.

Mr. Biden is in Europe for every week to attend the NATO and Group of seven summits and to fulfill with President Vladimir V. Putin of Russia in Geneva. He’s seemingly to make use of the journey to name on different nations to step up vaccine distribution.

In an announcement on Wednesday, Jeffrey D. Zients, the White Home official answerable for devising a world vaccination technique, mentioned Mr. Biden would “rally the world’s democracies round fixing this disaster globally, with America main the best way to create the arsenal of vaccines that can be crucial in our world struggle in opposition to Covid-19.”

The White Home is attempting to highlight its success in combating the pandemic — notably its vaccination marketing campaign — and use that success as a diplomatic device, particularly as China and Russia search to do the identical. Mr. Biden has been insistent that, in contrast to China and Russia, which have been sharing their vaccines with dozens of nations, the US won’t search to extract guarantees from international locations receiving American-made vaccines.

The 500 million doses nonetheless fall far wanting the 11 billion the World Well being Group estimates are wanted to vaccinate the world, however considerably exceed what the US has dedicated to share thus far. Different nations have been pleading with the US to surrender a few of its plentiful vaccine provides. Lower than 1 p.c of individuals are fully vaccinated in numerous African international locations, in contrast with 42 p.c in the US and the UK.

Advocates for world well being welcomed the information, however reiterated their stance that it’s not sufficient for the US to easily give vaccine away. They are saying the Biden administration should create the circumstances for different international locations to fabricate vaccines on their very own, together with transferring expertise to make the doses.

“The world wants pressing new manufacturing to provide billions extra doses inside a yr, not simply commitments to purchase the deliberate insufficient provide,” Peter Maybarduk, the director of Public Citizen’s Entry to Medicines program, mentioned in an announcement. He added, “We now have but to see a plan from the U.S. authorities or the G7 of the wanted ambition or urgency to make billions extra doses and finish the pandemic.”

The take care of Pfizer has the potential to open the door to comparable agreements with different vaccine producers, together with Moderna, whose vaccine was developed with American tax {dollars} — in contrast to Pfizer’s. As well as, the Biden administration has brokered a deal through which Merck will help produce Johnson & Johnson’s vaccine, and people doses may be obtainable for abroad use.

The USA has already contracted to purchase 300 million doses of the Pfizer-BioNTech vaccine, which requires two pictures, for distribution in the US; the 500 million doses are along with that, in accordance with individuals aware of the deal.

Neither Pfizer nor administration officers would say what the corporate is charging the federal government for the doses. Pfizer can be providing the Biden administration an choice to purchase much more doses at value to be donated abroad, in accordance with a number of individuals aware of the association.

For Pfizer, the choice to promote the Biden administration a lot provide with out making a revenue is a big step.

Its vaccine accounted for $3.5 billion in income within the first three months of this yr, practically 1 / 4 of Pfizer’s whole income. By some estimates, the agency earned roughly $900 million in pretax earnings from the vaccine in the course of the first quarter.

However the firm additionally confronted criticism that it was disproportionately aiding rich nations, regardless that Pfizer’s chief government, Albert Bourla, had promised in January to assist be certain that “growing international locations have the identical entry as the remainder of the world.”

For Mr. Biden, the settlement reveals that his administration is prepared to dip extra deeply into the nation’s treasury to assist out poorer international locations.

Final week, Mr. Biden mentioned the US would distribute 25 million doses this month to international locations within the Caribbean and Latin America; South and Southeast Asia; Africa; and the Palestinian territories, Gaza and the West Financial institution.

These doses are the primary of 80 million that Mr. Biden pledged to ship overseas by the top of June; three-quarters of them can be distributed by Covax. The remaining will go towards addressing urgent and pressing crises in locations like India and the West Financial institution and Gaza, administration officers have mentioned. Most of the 80 million doses have been made by AstraZeneca and are nonetheless tied up in a posh evaluation by the Meals and Drug Administration.

Mr. Biden has additionally dedicated to supporting a waiver of a world mental property settlement, which might make it tougher for firms to refuse to share their expertise. However European leaders are blocking the proposed waiver, and pharmaceutical firms are strongly against it. The World Commerce Group’s Council for Commerce-Associated Elements of Mental Property Rights is assembly this week to think about the waiver.

The president’s promise of vaccines for the worldwide market comes as he prepares to fulfill on Thursday with Prime Minister Boris Johnson of Britain, who has known as on leaders to decide to vaccinating everybody on the planet by the top of 2022. Mr. Biden’s announcement is prone to be welcome information for Mr. Johnson, whose critics have questioned the place the cash will come from to fulfill his pledge.

“The reality is that world leaders have been kicking the can down the highway for months — to the purpose the place they’ve run out of highway,” Edwin Ikhouria, the chief director for Africa on the ONE Marketing campaign, a nonprofit aimed toward eradicating world poverty, mentioned in an announcement on Wednesday.

About 64 p.c of adults in the US are at least partly vaccinated, and the president has set a purpose of bringing that quantity as much as 70 p.c by July 4. The tempo of vaccination has dropped sharply since mid-April, main the Biden administration to pursue a technique of better accessibility and incentives to achieve People who haven’t but gotten pictures.

Regardless of these efforts, there are unused vaccine doses that could go to waste. As soon as thawed, doses have a restricted shelf life and thousands and thousands might start expiring inside two weeks, in accordance with federal officers.

Offering equitable entry to vaccines has turn out to be one of the vital intractable challenges to reining within the pandemic. Wealthier nations and personal entities have pledged tens of thousands and thousands of doses and billions of {dollars} to shore up world provides, however the disparity in vaccine allocations thus far has been stark.

Dr. Tedros Adhanom Ghebreyesus, the director normal of the World Well being Group, warned this week that the world was dealing with a “two-track pandemic,” through which countries where vaccines are scarce will struggle with virus cases at the same time as better-supplied nations return to regular.

These lower-income international locations can be largely depending on wealthier ones till vaccines could be distributed and produced on a extra equitable foundation, he mentioned.

Daniel E. Slotnik contributed reporting from New York, and Michael D. Shear from Plymouth, England.

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