“It exceeds all expectations,” mentioned Dr. Kizzmekia S. Corbett, a viral immunologist and chief of a workforce that developed the vaccine on the infectious illness institute.

Greater than half of the individuals had unwanted side effects, together with fatigue, chills, complications, muscle aches and ache on the injection web site. Some had fever. One one who acquired the low dose developed hives and was withdrawn from the research. Not one of the unwanted side effects had been thought-about severe.

Specialists not concerned with the research mentioned the outcomes had been encouraging, however early. “Simply because you’ve got antibodies doesn’t imply you’re fully immune,” Dr. Rasmussen mentioned.

It’s doable, she mentioned, {that a} vaccine may not completely stop an infection, however that it would make the sickness much less extreme. “If it’s a alternative between a foul chilly and being on a ventilator, I’ll take the unhealthy chilly,” she mentioned.

Dr. Paul Offit, an infectious illness skilled on the College of Pennsylvania and Youngsters’s Hospital of Philadelphia, mentioned that the neutralizing antibodies and different immune responses had been an excellent signal, however that it was not recognized but whether or not they would truly shield folks in opposition to the virus, or how lengthy they might final. The unwanted side effects are a “small worth to pay” for cover in opposition to a doubtlessly extreme illness, he mentioned, although fever could also be a trigger for concern as soon as the vaccine is given to giant numbers of individuals.

“You at all times fear that fever, particularly excessive fever, might result in different issues,” Dr. Offit mentioned, including that solely a big managed research can decide whether or not the vaccine is actually protected and efficient.

In any other case, “it’s studying the tea leaves,” he mentioned. “You simply don’t know something till you do a Part three trial.”

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